Publications of Jens Claus Brüning
All genres
Journal Article (151)
2024
Journal Article
6 (3), pp. 473 - 493 (2024)
Reciprocal activity of AgRP and POMC neurons governs coordinated control of feeding and metabolism. Nature Metabolism
Journal Article
43 (4), 113960 (2024)
Activation of GFRAL+ neurons induces hypothermia and glucoregulatory responses associated with nausea and torpor. Cell Reports
Journal Article
384 (6694), pp. 438 - 446 (2024)
Food perception promotes phosphorylation of MFFS131 and mitochondrial fragmentation in liver. Science
Journal Article
15, 3443 (2024)
Single cell tracing of Pomc neurons reveals recruitment of ‘Ghost’ subtypes with atypical identity in a mouse model of obesity. Nature Communications
Journal Article
13 (1), 102 (2024)
An approach to intersectionally target mature enteroendocrine cells in the small intestine of mice. Cells 2023
Journal Article
381 (6665), eabl7398 (2023)
Integrative neurocircuits that control metabolism and food intake. Science
Journal Article
35 (5), pp. 786 - 806.e13 (2023)
Nutrient-sensing AgRP neurons relay control of liver autophagy during energy deprivation. Cell Metabolism
Journal Article
35 (4), pp. 571 - 584.e6 (2023)
Habitual daily intake of a sweet and fatty snack modulates reward processing in humans. Cell Metabolism
Journal Article
25 (1), pp. 20 - 29 (2023)
Sphingolipid subtypes differentially control proinsulin processing and systemic glucose homeostasis. Nature Cell Biology
Journal Article
14 (1), 7824 (2023)
CerS6-dependent ceramide synthesis in hypothalamic neurons promotes ER/mitochondrial stress and impairs glucose homeostasis in obese mice. Nature Communications
Journal Article
4 (1), 100897 (2023)
Circulating uridine dynamically and adaptively regulates food intake in humans. Cell Reports Medicine
Journal Article
5 (8), pp. 1352 - 1363 (2023)
Liraglutide restores impaired associative learning in individuals with obesity. Nature Metabolism
Journal Article
54 (11-12), pp. 1283 - 1295 (2023)
Hyperpolarized multi-organ spectroscopy of liver and brain using 1-C-13-pyruvate enhanced via parahydrogen. Applied Magnetic Resonance
Journal Article
71, 101707 (2023)
The long-lasting shadow of litter size in rodents: litter size is an underreported variable that strongly determines adult physiology. Molecular Metabolism
Journal Article
71 (4), pp. 1120 - 1141 (2023)
Early microglial response, myelin deterioration and lethality in mice deficient for very long chain ceramide synthesis in oligodendrocytes. Glia 2022
Journal Article
7 (21), e162753 (2022)
Dopamine-inhibited POMCDrd2+neurons in the ARC acutely regulate feeding and body temperature. JCI Insight
Journal Article
79 (8), 395 (2022)
Contribution of specific ceramides to obesity-associated metabolic diseases. Cellular and Molecular Life Sciences
Journal Article
130 (5), pp. 290 - 295 (2022)
Obesity - A Matter of Motivation? Experimental and Clinical Endocrinology & Diabetes
Journal Article
102 (3), pp. 560 - 576 (2022)
Caloric restriction reduces the pro-inflammatory eicosanoid 20-hydroxyeicosatetraenoic acid to protect from acute kidney injury. Kidney International
Journal Article
43 (2), pp. 314 - 328 (2022)
Arcuate nucleus-dependent regulation of metabolism - pathways to obesity and diabetes mellitus. Endocrine Reviews